Faculty of Medical and Health Sciences
Department of Pharmacology & Clinical Pharmacology, University of Auckland
Faculty of Medical and Health Sciences
Department of Pharmacology & Clinical Pharmacology, University of Auckland

MEDSCI 722 workshop timetable

Workshops are held on Fridays 11 am -1 pm in various rooms. See Room column below.

DNSR=Derek North Seminar Room, 12th floor, Auckland Hospital, 599-12069


Date Week Room Topic Resources Teaching staff
28 Jul 31 503-128 Introduction to course/revision
  • Clearance
  • NH
  • Volume
  • Absorption & half-life
  • Drug metabolism
  • Variability due to environmental differences
  • Variability due to genetic differences
  • Immediate drug effects
  • Delayed and cumulative drug effects
  • 04 Aug 32 503-128 PKPD variability
  • PKPD variability
  • NH
  • Population PKPD
  • 11 Aug 33 DNSR Disease progression and drug action
  • Clinical Pharmacology = Disease Progress + Drug Action
  • Disease Progress (Lecture 11 Aug 2017)
  • NH
  • Disease Progress Article
  • 18 Aug 34 502-B51 Drugs in the neonate & child
  • Drugs in the neonate & child
  • BA
  • Size and Maturity (PDF)
  • 25 Aug 35 503-128 Predicting and preventing adverse drug reactions and interactions
  • Predicting and preventing adverse drug reactions and interactions
  • MT
    01 Sep 36 503-128 Clinical trials: design, and analysis
  • Clinical trials: design, and analysis
  • NH
    Video cartoon :-)
  • Clinical drug development
  • Clinical measurement
  • Mid-semester break 4 Sep - 16 Sep
    22 Sep 39 DNSR Drug disposition in pregnancy
  • Drug disposition in pregnancy
  • AP
    29 Sep 40 DNSR  Drug Literature Evaluation  Drug literature evaluation
    Notes
    TS
    06 Oct 41 DNSR Class effects Class effects
    Class effects article
    NH
    13 Oct 42 503-128 Coursework presentations Group 1 NH
    20 Oct 43 503-128 Coursework presentations Group 2 NH
    27 Oct 44 503-128 Clinical pharmacology review NH
    TBA Final Exam TBA
    Grafton campus

    Teaching staff: NH - Nick Holford; BA - Brian Anderson; AP - Anna Ponnampalam; MT - Malcolm Tingle; TS - Trevor Speight 

    Suggested Reading Materials

    1. Kearns GL, Abdel-Rahman SM, Alander SW, Blowey DL, Leeder JS, Kauffman RE. Developmental pharmacology--drug disposition, action, and therapy in infants and children. N Engl J Med 2003; 349:1157-67
    2. Anderson BJ, Holford NHG. Mechanism based concepts of size and maturity in pharmacokinetics. Annual Review of Pharmacology and Toxicology 2008; 48: 303-32
    3. Anderson BJ, Holford NHG. Mechanistic basis of using body size and maturation to predict clearance in humans. Drug Metab Pharmacokinet 2009; 24 (1): 25-36
    4. Anderson BJ, Meakin GH.  Scaling for size; some implications for paediatric anaesthesia dosing.  Paediatr Anaesthesia 2002; 12: 205-219
    5. Holford NH . Dosing in children. Clin Pharm Ther 2010;87:367-70
    6. Holford, N. (2015). "Clinical pharmacology = disease progression + drug action." Br J Clin Pharmacol 79(1): 18-27.
    7. Holford, N., Y. A. Heo and B. Anderson (2013). "A pharmacokinetic standard for babies and adults." J Pharm Sci 102(9): 2941-2952.
    8. Anderson, B. J. and N. H. Holford (2013). "Understanding dosing: children are small adults, neonates are immature children." Arch Dis Child 98(9): 737-744.