Faculty of Medical and Health Sciences
Department of Pharmacology & Clinical Pharmacology, University of Auckland
Faculty of Medical and Health Sciences
Department of Pharmacology & Clinical Pharmacology, University of Auckland

MEDSCI 719 course details

Teaching staff

General questions regarding this course should be directed to the course director (Nick Holford).

Prof Nick Holford
Pharmacology & Clinical Pharmacology
Room: 503-229
Phone: +64 9 373 7599 ext 86730
Email: n.holford@auckland.ac.nz

Dr Jacqui Hannam
Pharmacology & Clinical Pharmacology
Room: 503-296
Phone: +64 9 923 2869
Email: j.hannam@auckland.ac.nz

Mr James Morse
Pharmacology & Clinical Pharmacology
Email: j.morse@auckland.ac.nz
Mr Conor O'Hanlon
Pharmacology & Clinical Pharmacology
Email: c.ohanlon@auckland.ac.nz
Mr Guangda Ma
Pharmacology & Clinical Pharmacology
Email: g.ma@auckland.ac.nz
Ms Arti Vaidya
Group Services Administrator
Email: arti.vaidya@auckland.ac.nz

In course weekly activities are taught in the 2 hour laboratory session. Students are expected to follow the instructions for each session (see Topic column in the Timetable) and complete the activities in their own time. Three in course activities are assessed by written assignments. The analyis of literature data topic is assessed by an oral presentation from each student in the 2 hour laboratory session and a final assessment writtten report. Note the written report is due after the oral presentation and typically the written report will reflect what was learned during disucssion of the oral presentation.


  1. 100% Coursework (three written reports of in course computer modelling assignments plus an oral presentation and a final assessment report).
    Sharing of data is only appropriate for the 2 compartment beaker experiment when students work in groups.
    Computation of results from data must be performed individually and written reports created in your own words. 
  2. Written reports are required for the following in course assignments. 
    1. In course assignment: 20% Time Course of Effect due date 17 Aug
    2. In course assignment: 20% Two Compartment Model due date 7 sep - changed to 14 Sept because of  campus lockdown
    3. In course assignment: 20% Population PD Model due date 19 Oct
    4. In course assignment: 5% Oral presentation of Analysis of Literature Data on 19 Oct
  3. Final Assessment: 35% Analysis of Literature Data with written report due date 5 Nov
  4. All reports (in course assignment and final assessment) should be submitted as a Microsoft Word document by email to Nick Holford. The email subject and the document file name should show the assignment number, topic and the student name e.g. "1 Time Course of Effect Nick Holford"

Plagiarism or failure to acknowledge quotes and sources of information is cheating.

When plagiarism is discovered no marks will be given and the incident will be reported to the University Education Committee.

Recommended reading

  1. Bonate P.L. Pharmacokinetic-pharmacodynamic modeling and simulation. Springer. New York, 2005
  2. Gabrielsson J, Weiner D. Pharmacokinetic and pharmacodynamic data analysis: concepts and applications.(5th Edition) Swedish Pharmaceutical Press, Stockholm, 2014
  3. Bourne DWA. Mathematical modelling of pharmacokinetic data. Technomic, Basel, 1995
  4. Rowland M, Tozer TN. Clinical Pharmacokinetics (2nd or 3rd Edition), Williams & Wilkins, Baltimore, 1995
  5. Schoenwald RD. Pharmacokinetics in drug discovery and development. CRC Press, Boca Raton, 2002
  6. CPT PSP Tutorials
  7. Basic concepts in population modeling, simulation and model-based drug development. Part 1 
  8. Basic concepts in population modeling, simulation and model-based drug development. Part 2 

Computing resources

Modelling assignments will use the computers in the Multidisciplinary Computing Laboratory and may also access other computers on campus from the Computing Lab machines. Students are expected to have access to the UOA domain.

Late submission of work/penalties

To apply for an extension, students need to contact the Course Coordinator and supply documentation (e.g. doctor’s certificate/collaborating note from a counsellor) before the due date.  Please note that your application is a request only and it should not be assumed that an extension will be granted. Retrospective approval for an extension will be given only in exceptional circumstances. 

Except where the Course Coordinator has authorised an extension of time for the submission of student work, work handed in after the deadline will incur a late penalty of 5% for each 12-hour period (or part thereof) that the assessment is overdue.  This applies to all written work, including but not limited to lab reports, essays, seminar papers / presentations, assignments, posters, etc. Submission of written work is only complete when an electronic copy has been submitted through the appropriate platform (e.g. Turnitin or Canvas). Please retain your submission confirmation e-receipt / take a time stamped screenshot as evidence of timely submission.  

Aegrotat or compassionate consideration for coursework

If you believe illness, injury or personal misfortune has affected the quality of your submitted work, you can apply for aegrotat or compassionate consideration

Inclusive Teaching and Teaching Students with Impairments

Guidelines on Inclusive Teaching and Teaching Students with Impairments include the words:

“Students are asked to discuss privately any impairment related requirements face –to-face and/or in written form with course convenor, lecturer or tutor.”

Please contact Nick Holford (course co-ordinator) if you have any impairment related requirements.

Canvas & Piazza

Course details are also maintained on Canvas. Please make sure you are able to log on to Canvas. Class announcements will be made using Canvas.

Piazza is used for class discussion from the Piazza link on Canvas. The system is designed to assist you in getting help quickly and efficiently from classmates, graduate teaching assistants, and faculty. Rather than emailing questions to the teaching staff, you are encouraged you to post your questions on Piazza. If you have any problems or feedback for the developers, email team@piazza.com.

Find our class signup link at: https://piazza.com/aucklanduni.ac.nz/semester22020/medsci719